third diabetic syndrome

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A form of DM described in young black Pts which may differ from type 1 DM, as 1. 30-40% have HLA-DR3 or HLA-DR4 antigen, in contrast to whites, 95% of whom express HLA-DR3 or -DR4 2. 40% have islet cell antibodies, versus 70-80% of whites 3. Most Pts are well controlled with diet or oral anti-diabetics, 4. AD inheritance pattern

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