thiothixene


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thiothixene

 [thi″o-thik´sēn]
an antipsychotic agent that is a thioxanthene derivative; administered orally or intramuscularly as the base or the hydrochloride salt.

thiothixene

/thio·thix·ene/ (-thik´sēn) a thioxanthene derivative, used as the base or the hydrochloride salt for the treatment of psychotic disorders.

thiothixene

(thī′ō-thĭk′sēn′)
n.
An antipsychotic drug, C23H29N3O2S2, used primarily in the treatment of schizophrenia.

thiothixene

[-thī′ksēn]
a thioxanthene antipsychotic.
indications It is prescribed in the treatment of acute agitation and mild-to-severe psychotic disorders.
contraindications Parkinson's disease, concurrent administration of central nervous system depressants, hepatic or renal dysfunction, severe hypotension, or known hypersensitivity to this drug or to phenothiazine medications prohibits its use. It is not recommended for children under 12 years of age.
adverse effects Among the more serious adverse effects are hypotension, hepatotoxicity, extrapyramidal reactions, blood dyscrasias, and hypersensitivity reactions.

thiothixene (thī´ōthik´sēn),

n brand name: Navane;
drug class: thio-xanthene/antipsychotic;
action: depresses the cerebral cortex, hypothalamus, and limbic system, which control activity and aggression; blocks neurotransmission produced by dopamine at the synapse;
uses: treatment of psychotic disorders, schizophrenia, and acute agitation.
References in periodicals archive ?
Borderline and schizotypal personality disorders treated with low-dose thiothixene versus placebo.
Response of borderline and schizotypal patients to small doses of thiothixene and haloperidol.
Amoxicillin-clavulanate * Augmentin Carbamazepine * Tegretol Chlorpromazine * Thorazine Ciprofloxacin * Cipro Citalopram * Celexa Donepezil * Aricept Galantamine * Reminyl Haloperidol * Haldol Levofloxacin * Levaquin Memantine * Namenda Olanzapine * Zyprexa Risperidone * Risperdal Rivastigmine * Exelon Thioridazine * Mellaril Thiothixene * Navane Valproate * Depakote
She had previous trials of several antipsychotics, including quetiapine, thiothixene, thioridazine, trifluoperazine, chlorpromazine, and haloperidol, all of which were ineffective and poorly tolerated because of serious side effects.
In these select few--who also had not responded to antidepressants or mood stabilizers--I have found thiothixene to be especially helpful to rapidly reduce anger.