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thiothixene

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thiothixene /thio·thix·ene/ (-thik´sēn) a thioxanthene derivative, used as the base or the hydrochloride salt for the treatment of psychotic disorders.
thi·o·thix·ene (th-thksn)
n.
An antipsychotic drug that is given orally and intramuscularly, used primarily in the treatment of schizophrenia.

thiothixene
[-thī′ksēn]
a thioxanthene antipsychotic.
indications It is prescribed in the treatment of acute agitation and mild-to-severe psychotic disorders.
contraindications Parkinson's disease, concurrent administration of central nervous system depressants, hepatic or renal dysfunction, severe hypotension, or known hypersensitivity to this drug or to phenothiazine medications prohibits its use. It is not recommended for children under 12 years of age.
adverse effects Among the more serious adverse effects are hypotension, hepatotoxicity, extrapyramidal reactions, blood dyscrasias, and hypersensitivity reactions.

thiothixene (thī´ōthik´sēn),
n brand name: Navane;
drug class: thio-xanthene/antipsychotic;
action: depresses the cerebral cortex, hypothalamus, and limbic system, which control activity and aggression; blocks neurotransmission produced by dopamine at the synapse;
uses: treatment of psychotic disorders, schizophrenia, and acute agitation.


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