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thioguanine/thio·gua·nine/ (-gwah´nēn) an antineoplastic derived from mercaptopurine; used in the treatment of acute myelogenous leukemia.
a purine analog antagonist, an antineoplastic that acts as an antimetabolite.
indications It is prescribed in the treatment of a variety of malignant neoplastic diseases, especially acute and chronic myelogenous leukemias.
contraindications Known hypersensitivity or resistance to this drug prohibits its use. It is not given during pregnancy.
adverse effects Among the most serious adverse effects are bone marrow depression, GI distress, and stomatitis.
thioguanineLanvis® Oncology An antimitotic purine analogue, used against AML. See Purine.
thioguanineTioguanine, a drug used in the treatment of acute myeloblastic leukaemia. A brand name is Lanvis.
an antineoplastic (2-aminopurine-6-thiol) used in the treatment of leukemia.