thiabendazole

thiabendazole /thi·a·ben·da·zole/ (thi″ah-ben´dah-zōl) a broad-spectrum anthelmintic used in the treatment of strongyloidiasis, trichinosis, and cutaneous or visceral larva migrans.

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thi·a·ben·da·zole (th-bnd-zl)

n.

A white compound used as an antifungal agent and as an anthelmintic; it is effective against a broad spectrum of infectious agents.

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thiabendazole

[thī′əben′dəzōl]

an anthelmintic with anti-inflammatory, antipyretic, and analgesic effects.

indications It can be prescribed in the treatment of a range of worm infestations, including hookworms, roundworms, and pinworms, and was the drug of choice for threadworms until recently. Other drugs have fewer adverse effects.

contraindications Erythema multiforme, Stevens-Johnson syndrome, or known hypersensitivity to this drug prohibits its use.

adverse effects Among the more serious adverse effects are anorexia, central nervous system effects, severe GI disturbances, dizziness, and hypotension. Approximately one-third of people are incapacitated by this drug for several hours after administration.

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thiabendazole [thi″ah-ben´dah-zōl]

a broad-spectrum anthelmintic used in the treatment of cutaneous larva migrans, visceral larva migrans, strongyloidiasis, and trichinosis.

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thiabendazole (thī´ben´dzōl),

n an anthelmintic agent most effective against infection with the roundworm
Strongyloides. Its effectiveness in treating other roundworm infections is varied.

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thiabendazole

a very safe and effective, broad-spectrum anthelmintic used widely in sheep. Also used extensively in horses in combination with piperazine. Poisoning with thiabendazole has been recorded but it is a very unusual occurrence requiring a massive overdose. It is capable of causing incoordination and collapse initially, and subsequently toxic nephrosis with terminal uremia.