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therapeutic gain

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therapeutic gain,
the ratio of the biologic effect of a therapy on a tumor compared with the effect on surrounding normal tissue. Higher therapeutic gains mean lower complications of therapy.

therapeutic gain
Placebo-subtracted response Research The response in a treatment group minus the response in a control/placebo group. See Placebo effect.


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Yes, you have a double therapeutic gain as it makes tumor cells more sensitive to radiation, and makes normal tissue less sensitive
Chapters cover the basic radiobiology of continuous irradiation, therapeutic gain models for continuous irradiation, permanent seed implants, properties of small-volume tumors and subclinical disease, dose and dose-volume inhomogeneities, tissue architecture and its effect on normal tissue and tumor response to irradiation, and three-dimensional volume effects.
Resveratrol seems to have a therapeutic gain by making tumor cells more sensitive to radiation and making normal tissue less sensitive.
 
 
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