therapeutic cloning


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therapeutic cloning

n.
The production of embryonic stem cells for use in replacing or repairing damaged tissues or organs, achieved by transferring a diploid nucleus from a body cell into an egg whose nucleus has been removed and by harvesting cells from the resulting blastocyst.
Cloning in which the nucleus of a somatic—i.e., non-germinal/reproductive—cell is transferred into an egg from which the nucleus has been previously removed, in order generate an embryonic stem-cell line, which has the advantage of pluripotency—i.e., the ability to differentiate along multiple pathways except the reproductive pathway

therapeutic cloning

Molecular medicine The cloning of human cell lines to replace nonfunctional tissue. See Cloning.

therapeutic cloning

medical and scientific applications of cloning (see CLONE that do not result in the production of genetically-identical foetuses, but rather involve the use of STEM CELLS grown IN VITRO to provide specific cell lines. Essentially a form of TISSUE CULTURE to produce human stem cells and ultimately TISSUES and ORGANS for transplantation. Therapeutic cloning is so called because of the potential therapeutic benefits stem cells possess to alleviate or even cure such debilitating diseases as PARKINSON'S DISEASE, ALZHEIMER'S DISEASE,

DIABETES, stroke, BONE diseases, HEART diseases and SPINAL CORD injuries. By culturing stem cells in the presence of, for example, specific HORMONES they may be able to differentiate into different cell types, including NERVE CELLS for treatment of Parkinson's disease, INSULIN-producing ISLET cells for diabetes, or heart muscle cells for heart diseases. Such an approach would be likely to avoid problems of transplant rejection (see TRANSPLANTATION), if the cells are genetically-identical to the patients’ own. Ethical problems (see BIOETHICS).surround the use of embryonic stem cells in therapeutic cloning because a human embryo has to be found. This may be from a frozen embryo, surplus to requirements for IVF treatment, an aborted FOETUS or an EMBRYO produced using nuclear transfer procedures.Sometimes therapeutic cloning is called spare part cloning.

References in periodicals archive ?
Pursuing medical advances through therapeutic cloning can help millions of those who suffer from diseases and injuries to one day have fuller memories, be able to walk, be pain free, and not suffer from chronic heart disease.
Human cloning prohibitions also apply to therapeutic cloning in Iowa and Michigan.
Though therapeutic cloning could generate a greater demand for embryos, thus creating an environment where commodification is more likely, the act of therapeutic cloning does not commodify the embryo.
If he had instead issued a strong call for therapeutic cloning from donor eggs, coupled with an equally strong sanction against the intentional creation of new fertilized eggs for research purposes and the implantation of any experimentally modified human embryos into a woman's body, he would have opened up a most promising second line of basic research for a ll, instead of restricting federal support to a set of cell lines tainted by the crushed intentions of their donors that they become people, the certainty of immune rejection down the road, and the commercial implications of a premature monopoly.
Canada's position regarding therapeutic cloning research can also be seen to call for international involvement.
She added: "It is also important to remember that therapeutic cloning is just one area of stem cell research.
Last year Professor Hwang's team announced the creation of the first line of embryonic stem cells derived from the therapeutic cloning of embryos.
Backers of this resolution argue that, while the world is divided over therapeutic cloning, a consensus against reproductive cloning already exists, and the United Nations could and should move quickly to produce a convention against it.
Last night Dr Reid promised: 'We will not support any moves to ban therapeutic cloning because we believe it offers huge potential to develop new cures for life threatening diseases such as Parkinson's and Alzheimer's.
However, therapeutic cloning offers enormous potential to develop cures for diseases such as Alzheimer's,Parkinson's,and heart disease which affect millions of people.
Therapeutic cloning seeks not to create a new human being, but cells that could be used in the treatment of disease.
The Globe, in fact, objected to the Minister's desire to ban therapeutic cloning involving the creation of embryos for research purposes.