thalassaemia


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Related to thalassaemia: Thalassaemia minor

thal·as·se·mi·a

, thalassanemia (thal'ă-sē'mē-ă, -ă-să-nē'mē-ă)
Any of a group of inherited disorders of hemoglobin metabolism in which there is impaired synthesis of one or more of the polypeptide chains of globin; several genetic types exist, and the corresponding clinical picture may vary from barely detectable hematologic abnormality to severe and fatal anemia. People of Mediterranean, extraction are more often affected than others by this type of anemia.
Synonym(s): thalassaemia, thalassanaemia.
[G. thalassa, the sea, + haima, blood]

thalassaemia

One of several hereditary abnormalities of synthesis of the globin chains of HAEMOGLOBIN leading to severe ANAEMIA. The disorder is common in the area surrounding the Mediterranean sea. When the abnormality is HETEROZYGOUS (thalassaemia minor), disability is minimal, but when HOMOZYGOUS (thalassaemia major), anaemia may be severe with breathlessness, jaundice, spleen enlargement and sometimes physical and mental retardation. Treatment is by blood transfusion and bone marrow transplantation. From the Greek words thelazia , the sea, and haima , blood.

thal·as·se·mi·a

, thalassanemia (thal'ă-sē'mē-ă, -ă-să-nē'mē-ă)
Any of a group of inherited disorders of hemoglobin metabolism with impaired synthesis of one or more polypeptide chains of globin; several genetic types exist.
Synonym(s): thalassaemia, thalassanaemia.
[G. thalassa, the sea, + haima, blood]
References in periodicals archive ?
He said that thalassaemia was a dangerous disease as its patients lived for longer time as compared to that of cancer and Aids.
Salma said with the spotlight on blood borne diseases like Hepatitis C and Hepatitis-B, there is a general tendency in the country to ignore the threats of Thalassaemia.
Keywords: Thalassaemia, Awareness, Attitude, Carrier screening, Genetic disease, Prevention.
As thalassaemia poses demanding challenge in terms of managing with limited resources in a country like Bangladesh, awareness, screening of carriers and prevention of births of the thalassaemic children by prenatal diagnosis are important.
The Khyber-Pakhtunkhwa government, which runs a cohesive programme for thalassaemia, HIV and hepatitis and offers free blood screening, aims to pass a law to make screening mandatory for couples before marriage.
May 8 is an opportunity to raise awareness around the world for countries to introduce national programmes of prevention and treatment of thalassaemia, said the executive director of TIF, Dr Androulla Eleftheriou.
The incidence of Beta thalassaemia trait and sickle cell anaemia varies between 3 to 17% and 1 to 44% respectively.
MUHAMMAD IQBAL: I will emphasize two aspects one is awareness about the thalassaemia disease so that everyone is tested for thalassaemia minor status with a view to prevent marriages between two minors.
HE is a rare entity that sometimes present with other haemoglobin disorders like beta thalassaemia, sickle cell anaemia and Hb C.
The double heterozygous condition of Hb E/[beta]-thalassaemia is, however, a major public health hazard in the Far East, India, Pakistan and Bangladesh, with a clinical picture akin to that of thalassaemia major.
11 undergo mutations that cause thalassaemia with inadequate production of b-gobin chains of haemoglobin, with excessive alpha globin chains8.
PESHAWAR -- Chief Minister Khyber Pakhtunkhwa Pervez Khattak has expressed his concern over the rapidly spreading Thalassaemia disease in the country as more than six thousand children are falling prey to the deadly ailment every year.