tetrandrine

tetrandrine

(tĕt-tran-drēn'),
Blocker of L-type calcium channels, also blocks the calcium-activated potassium channel. May also have some immunosuppressant activity.
References in periodicals archive ?
tetrandrine, a bisbenzylisoquinoline alkaloid has been found to induce apoptosis at a high concentration (30 [micro]M) by repressing AKT activity in HCC cells.
Tetrandrine blocks T and L calcium channels, interferes with the binding of diltiazem and methoxyverapamil at calcium-channel binding sites, and suppresses aldosterone production.
Tetrandrine is a bisbenzylisoquinoline alkaloid isolated from the dried root of Stephania tetrandra.
A small molecule called Tetrandrine derived from an Asian herb has shown to be a potent small molecule inhibiting infection of human white blood cells in vitro or petri dish experiments and prevented Ebola virus disease in mice.
Tetrandrine is derived from the root of a medicinal herb, Stephania tetrandra, commonly known as "han fang ji".
Evaluation of the novel anti-inflammatory agent tetrandrine as a pulpotomy medicament in a canine model.
Although magnetite nanoparticles loaded with doxorubicin and tetrandrine were used against K562 leukemia cells as a new strategy to inhibit drug resistance (16), (17).
Tetrandrine and related bis-benzylisoquinoline alkaloids from medicinal herbs: Cardiovascular and others effects and mechanisms of action.
In vitro inhibition of proliferation of HL-60 cells by tetrandrine and Coriolus versicolor peptide derived from Chinese medicinal herbs.
Inhibitory action of tetrandrine on macrophage production of interleukin-1 (IL-l)-like activity and thymocyte proliferation.
Tetrandrine, an alkaloid found in Stephania japonica, has anti-inflammatory activity.