tetracyclic antidepressant


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tet·ra·cy·clic an·ti·de·pres·sant

a class of antidepressants similar to the tricyclic antidepressants and also related to the phenothiazine antipsychotics.

tetracyclic antidepressant

(tĕt′rə-sī′klĭk, -sĭk′lĭk)
n.
Any of a class of antidepressants, such as maprotiline, whose chemical structure includes four benzene rings.

tetracyclic antidepressant

Any of a class of antidepressant agents whose chemical structure has four fused rings. These drugs block the reuptake of norepinephrine and serotonin at nerve endings.
See also: antidepressant
References in periodicals archive ?
The antidepressants currently prescribed for the treatment of MDD comprise eight main classes: The monoamine oxidase inhibitors (MAOIs), norepinephrine-dopamine reuptake inhibitors (NDRIs), serotonin modulators (SM), noradrenergic and specific serotonergic antidepressants (NaSSAs), serotonin-norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), and tetracyclic antidepressants (TeCAs).
Sexual side effects are most often associated with serotonin and norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSR1s), monoamine oxidase inhibitors (MAOIs) and tricyclic and tetracyclic antidepressants.
Randomized placebo-controlled trials with tricyclic and tetracyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and monoamine oxidase inhibitors (MAOIs) were analyzed.