tetanus and diphtheria toxoids

Also found in: Dictionary, Thesaurus, Financial, Encyclopedia.
Related to tetanus and diphtheria toxoids: varicella, pertussis

tetanus and diphtheria toxoids (Td)

an active immunizing agent containing detoxified tetanus and diphtheria toxoids that slowly produce an antigenic response to the diseases.
indications This drug is used for prophylaxis when treating wounds and is the preferred method for immunization against tetanus and diphtheria in adults and children over 7 years of age. Younger children should be treated with diphtheria, pertussis, and tetanus trivalent vaccine.
contraindications Immunosuppression, concomitant use of corticosteroids, or acute infection prohibits the use of this drug.
adverse effects Among the most serious adverse effects are allergic reactions and stinging at the site of injection.
References in periodicals archive ?
For active tetanus immunization in wound management of patients 7 years of age and older, a preparation containing tetanus and diphtheria toxoids is preferred instead of single-antigen tetanus toxoid to enhance diphtheria protection.
An adolescent-adult formulation tetanus and diphtheria toxoids adsorbed combined with acellular pertussis vaccine has comparable immunogenicity but less reactogenicity in children 4-6 years of age than a pediatric formulation acellular pertussis vaccine and diphtheria and tetanus toxoids adsorbed combined with inactivated poliomyelitis vaccine.
Deferral of routine booster doses of tetanus and diphtheria toxoids for adolescents and adults.
Update on the supply of tetanus and diphtheria toxoids and of tetanus and diphtheria toxoids and acellular pertussis vaccine.
A shortage of tetanus and diphtheria toxoids (Td) and tetanus toxoid (TT) in the United States has resulted because one of two manufacturers discontinued production of tetanus toxoid-containing products (1).
Public Health Service learned of a shortage of tetanus and diphtheria toxoids (Td) and tetanus toxoid (TT) resulting from decreased production of these vaccines by the two U.
Atemporary shortage of adult tetanus and diphtheria toxoids (Td) in the United States has resulted from two coincident situations: 1) a decrease in the number of lots released by Wyeth Lederle (Pearl River, New York), and 2) a temporary decrease in inventory of vaccine following routine maintenance activities at the production facilities by Aventis Pasteur (Swiftware, Pennsylvania) that lasted longer than anticipated.
At its meeting on October 19-20, 1994, the Advisory Committee on Immunization Practices (ACIP) adopted the recommendation that, for their patients aged 50 years, health-care providers 1) review adult vaccination status, 2) administer tetanus and diphtheria toxoids as indicated, and 3) determine whether a patient has one or more risk factors that indicate a need to receive one dose of pneumococcal vaccine and begin annual influenza vaccination.
She had received five doses of diphtheria and tetanus toxoids and pertussis vaccine (DTP) during childhood and an adult formulation tetanus and diphtheria toxoids (Td) booster in August 1991.