testes determining factor

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testes determining factor (TDF)

[tes′tēz]

a gene on the Y chromosome that is believed to determine male sexual development. Individuals with the normal female sex chromosome combination (XX) may develop as males if the TDF gene has migrated to one of the X chromosomes. Also, individuals with the normal male sex chromosome pair (XY) may develop as females if the TDF gene is missing from the Y chromosome.

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