termination codon


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Related to termination codon: stop codon, Amber codon, opal codon

ter·mi·na·tion co·don

trinucleotide sequence (UAA, UGA, or UAG) that specifies the end of translation or transcription. Compare: amber codon, ochre codon, umber codon.

termination codon

termination codon

[tur′minā′shən]
a three-nucleotide sequence (UAA, UAG, or UGA) in messenger RNA that specifies the end of the sequence of amino acids in a polypeptide.

ter·mi·na·tion co·don

(tĕr'mi-nā'shŭn kō'don)
Trinucleotide sequence (UAA, UGA, or UAG) that specifies the end of translation or transcription.
Compare: amber codon, ochre codon, umber codon
Synonym(s): termination signal.

termination codon

See STOP CODON.

termination codon

see NONSENSE CODON.

codon

a triplet in a chain of nucleic acids in mRNA that specifies the order in which amino acids are added. The codon triplet pairs with a sequence of three complementary nucleotides, called the anticodon, present in the anticodon arm of tRNA. Called also triplet. See also deoxyribonucleic acid.

start codon
see initiation codon.
stop c's
three codons, UAG, UAA and UGA, also referred to as amber, ochre and opal codons, in mRNA which terminate translation.
termination codon
see stop codons (above).
References in periodicals archive ?
Timor Bassov from the Technion - Israel Institute of technology - enabling selective and safe ribosomal readthrough of premature termination codons for the treatment of nonsense genetic diseases.
R]) promote the synthesis of mRNAs in which the leaderless AUG triplets are in-frame with termination codons anywhere from 2 to 9 codons downstream.
R]' mRNAs) have AUG triplets which are blocked by in-frame termination codons upstream of the coding regions for their known gene products.
If a 5'-proximal AUG triplet can serve as a sufficient translational initiation signal, then any AUG sequence positioned in this manner might conceivably be translated, mRNA conformation permitting, regardless of whether or not the utilized start codon is part of a legitimate open reading frame ending with one of the three possible termination codons.
The results of the multiple-dose study demonstrate the safety of PTC124 at the studied doses, as well as its specificity in reading through premature termination codons," said Langdon L.