Although the placental membrane is relatively thick and somewhat resistant to medication transfer during the first trimester, many major teratogenic
effects still occur as a result of medication exposure during this critical organ formation period.
It shows teratogenic
effects like CNS malformations and some types of urinogenital abnormalities (Haring et al.
MK-801, agmatine, eliprodil, memantine) during the withdrawal period, can attenuate some of alcohol's teratogenic
1), (4-6) Various teratogenic
agents, maternal diabetes, caudal regression syndrome and nutritional deficit have been suggested as possible aetiological factors.
If we want to develop] a new drug devoid of teratogenic
activity, it is important to understand [this] mechanism.
11 Family physicians perceived risk to be high, with 61% estimating the teratogenic
risk following abdominal CT to be 5% or greater and 44% estimating the risk following an abdominal X-ray to be 5% or greater.
Cytotoxic drugs are drugs that have a deleterious effects upon cells and many have been found to be mutagenic, teratogenic
However, another possible primary cause for such lesions is exposure to teratogenic
toxins, and this alone should warrant ongoing monitoring of breeding populations of little penguins and other species of high conservation status, especially those close to potentially contaminated major industrial areas such as Cockburn Sound near Penguin Island.
As CellCept has been shown to have teratogenic
effects in animals at subclinical doses on a body surface area basis, it may cause fetal harm when administered to a pregnant woman.
Because of the emphasis placed on the teratogenic
effects and the potential link to depression and increased suicidal ideation with use of isotretinoin, other side effects may go unnoticed.
Valproate poses by far the greatest teratogenic
risk of all the commonly prescribed antiepileptic drugs, according to Dr.
He also discusses the genesis of the EPA ban on DDT, a ban that was put in place despite the fact that EPA examiner Edmund Sweeney concluded: "DDT is not a carcinogenic, mutagenic, or teratogenic
hazard to man.