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telbivudine

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telbivudine,
an antiretroviral.
indication This drug is used in the treatment of hepatitis B.
contraindications Lactation and known hypersensitivity to this drug prohibit its use.
adverse effects Adverse effects of this drug include weakness, taste change, hearing loss, photophobia, abdominal pain, hepatomegaly, lactic acidosis, myalgia, arthralgia, muscle cramps, and cough. Common side effects include fever, headache, malaise, dizziness, insomnia, nausea, vomiting, diarrhea, anorexia, and rash.


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NUCLEOSIDE ANALOGUES: LAMIVUDINE, EMTRICITABINE, TELBIVUDINE AND ENTECAVIR LAMIVUDINE The first nucleoside analogue approved for the treatment of chronic hepatitis B was lamivudine (3TC).
Novartis Pharmaceuticals Canada and Health Canada notified health care professionals March 7 of an increased risk of peripheral neuropathy observed in chronic hepatitis B patients treated with Sebivo (telbivudine) in combination with Pegasys (peginterferon alfa-2a), compared to the interferon or telbivudine alone, during a controlled pilot clinical trial.
Since 1996, four oral antiviral medications have been approved by the Food and Drug Administration for treatment of hepatitis B: lamivudine, adefovir dipivoxil, entecavir and telbivudine.
 
 
 
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