tazobactam


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tazobactam

 [taz″o-bak´tam]
a β-lactamase inhibitor having antibacterial actions and uses similar to those of sulbactam; used as the sodium salt.

tazobactam

/taz·o·bac·tam/ (taz″o-bak´tam) a β inhibitor having antibacterial actions and uses similar to those of sulbactam; used as the sodium salt.

tazobactam

(tā′zō-băk′tăm)
n.
A compound, C10H12N4O5S, that inhibits action of the enzyme beta-lactamase, thus counteracting bacterial resistance to beta-lactam antibiotics. It is used in its sodium form in combination with piperacillin to treat infections caused by antibiotic-resistant bacteria.

tazobactam

[taz′o-bak′tam]
a beta-lactamase inhibitor having antibacterial actions and uses similar to those of sulbactam. It is used as the sodium salt.

tazobactam

A beta-lactamase inhibitor penicillin antibiotic. A brand name is Tazocin.

tazobactam

a penicillanic acid sulfone derivative, similar to sulbactam; often combined with other antibiotics to extend their spectrum of activity.
References in periodicals archive ?
Randomization placed 289 patients in the ertapenem group and 287 in the piperacillin plus tazobactam group.
This can be explained by the fact that AmpC [beta]-lactamase producers are more susceptible to tazobactam as compared to clavulanic acid (4).
Tazobactam does not restore the activity of piperacillin, or even degrade it, probably because of the induction of p-lactamase.
It is an injectable combination product that consists of piperacillin (an extended-spectrum penicillin) and tazobactam (a beta-lactamase inhibitor).
Cubist's CXA-201 is a first-line intravenous antibiotic combination of a novel cephalosporin (CXA-101) and a generic U-lactamase inhibitor - tazobactam - for the treatment of serious Gram negative bacterial infections.
Alcohol isoprolico gallon 95%,blister dexametasona 2ml 4mg 7ml,road piperacillin + tazobactam 4.
13) Tazobactam does not inhibit these chromosomal enzymes and therefore piperacillin-tazobactam is not appropriate for such infections.
Initial treatment with piperacillin/ tazobactam was based on the preliminary report of gram-negative bacilli, but later antimicrobial susceptibility testing showed this isolate to be susceptible to this agent.
Tenders are invited for Piperacillin Plus 4G Tazobactam 0.
ESBLs are enzymes distributed worldwide (5) that hydrolyze oxyimino-cephalosporins and monobactams and are susceptible to [beta]-lactamase inhibitors such as clavulanic acid and tazobactam.
The current Cubist clinical development pipeline includes CXA-201, a novel cephalosporin in combination with tazobactam in development for the treatment of certain serious infections caused by multi-drug resistant (MDR) Gram-negative organisms.