takotsubo cardiomyopathy


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A non-ischaemic cardiomyopathy most common in post-menopausal women, which is characterised by a sudden temporary weakening of the myocardium triggered by physical or emotional stress—e.g., death of a loved one—hence the alternate term, broken heart syndrome
Pathogenesis High serum catecholamines—adrenaline/ epinephrine
Diagnosis Negative coronary angiogram
Prognosis If the individual survives the initial event, the left ventricular function improves within 2 months

takotsubo cardiomyopathy

Reversible dysfunction of the left ventricle. It may be the cause of transient heart failure that occurs after exceptionally stressful events. The heart in such instances takes on a rounded shape with a narrow neck, resembling a traditional Japanese lobster trap (takotsubo). It is informally called broken-heart syndrome.
Synonym: apical ballooning syndrome; stress-induced cardiomyopathy; transient left ventricular apical ballooning
See also: cardiomyopathy
References in periodicals archive ?
These findings were consistent with Takotsubo cardiomyopathy and the patient was managed conservatively.
A new ECG criterion to identify takotsubo cardiomyopathy from anterior myocardial infarction: role of inferior leads.
Takotsubo cardiomyopathy is a syndrome of acute, usually reversible LV systolic dysfunction in the absence of obstructive coronary artery disease.
Many studies report that the underlying factor behind takotsubo cardiomyopathy might be emotional-stress-induced and neurohumoral-induced myocardial infarction.
Recurrence of takotsubo cardiomyopathy with variant forms of left ventricular dysfunction.
Acute Subarachnoid Hemorrhage and Cardiac Abnormalities: Takotsubo Cardiomyopathy or Neurogenic Stunned Myocardium?
At first, she thought that she might be having a heart attack but further medical tests at Memorial Hermann Heart & Vascular Institute-Texas Medical Center revealed that she was suffering from Takotsubo cardiomyopathy or broken-heart syndrome.
Takotsubo cardiomyopathy was not considered because of significantly elevated value of cardiac enzyme, severer spasm of coronary arteries, and absence of stressful trigger.
In fact cases of what is now called Takotsubo cardiomyopathy have been reported all over the world after a Japanese physician first reported the cases of relatively young females presenting with an unusual case of heart failure following an intense emotional stress such as breaking off with their spouses or boyfriends.
Dr Alexander Lyon, a senior lecturer at London's Imperial College and consultant cardiologist at the Royal Brompton Hospital, said this may have been a case of Takotsubo cardiomyopathy, a condition also known as broken heart syndrome when triggered by bereavement.
Electrocardiographic changes in Takotsubo cardiomyopathy.