tachyphylaxis

tachyphylaxis /tachy·phy·lax·is/ (-fĭ-lak´sis)

1. rapid immunization against the effect of toxic doses of an extract or serum by previous injection of small doses of it.

2. rapidly decreasing response to a drug or physiologically active agent after administration of a few doses.tachyphylac´tic

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tach·y·phy·lax·is (tk-f-lkss)

n.

1. Rapid desensitization to a pharmacologically or physiologically active substance, produced by inoculation with a series of small doses.

2. A rapidly decreasing response to a drug following its initial administration.

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tachyphylaxis

[tak′ēfəlak′sis]

Etymology: Gk, tachys + phylax, guard

1 (in pharmacology) a phenomenon in which the repeated administration of some drugs results in a rapidly appearing and marked decrease in effectiveness.

2 also called mithridatism. (in immunology), a rapidly developing immunity to a toxin because of previous exposure, such as from previous injection of small amounts of the toxin (named for Mithridates VI who used the technique to survive an assassination attempt).

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tachyphylaxis (ta·kē·flakˑ·sis),

n swiftly developed tolerance to a drug or toxin achieved through repeated exposure to minute doses.

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tachyphylaxis (tak´flak´sis),

n 1. the rapid development of tolerance on administration of closely spaced successive doses of a drug or poison.
2. a decreasing response that follows consecutive injections at short intervals.

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tachyphylaxis

1. rapid immunization against the effect of toxic doses of an extract by previous injection of small doses of it.

2. rapidly decreasing response to a drug or physiologically active agent after administration of a few doses.