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t-PA |
Also found in: Acronyms | 0.01 sec. |
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t-PA tissue plasminogen activator. t-PA Activase®, Alteplase®, tissue-plasminogen activator Cardiology A thrombolytic that upregulates fibrinolysis, activating conversion of plasminogen to plasmin, an enzyme that degrades fibrin clots, fibrinogen,
and other clotting factors, ergo reperfusing Pts with acutely occluded coronary arteries; SK has a half-life of 6-8 minutes, an expected 60-80% rate of reperfusion, is nonallergenic and nonantigenic, evokes little hypotension, and is theoretically,
more clot specific. See Thrombolytic therapy. Cf APSAC, Streptokinase. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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