systemic juvenile idiopathic arthritis


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Related to systemic juvenile idiopathic arthritis: juvenile rheumatoid arthritis

systemic juvenile idiopathic arthritis

A form of JIA that accounts for 20% of all cases; boys are affected 60% of the time. Fever and rash may be the presenting symptoms, either with or without joint involvement. Ultimately, 25% of these children develop severe arthritis.
See also: arthritis
References in periodicals archive ?
Diagnosis of systemic juvenile idiopathic arthritis (From: Petty RE, et al.
Radiologic analysis of the effect of tocilizumab on hands and large joints in children with systemic juvenile idiopathic arthritis.
Coverage of the Systemic Juvenile Idiopathic Arthritis (SJIA) pipeline on the basis of route of administration and molecule type.
Efficacy and safety of canakinumab, a long acting fully human anti-interleukin-1[eth] antibody, in systemic juvenile idiopathic arthritis with active systemic features: results from a Phase III study.
In addition to ongoing studies in CAPS, clinical trials are also under way with Ilaris in systemic juvenile idiopathic arthritis (SJIA), and more common disorders such as some forms of gout, chronic obstructive pulmonary disorder (COPD) and type 2 diabetes.
Food and Drug Administration (FDA) approved ACTEMRA (tocilizumab) for the treatment of active Systemic Juvenile Idiopathic Arthritis (SJIA) in patients two years of age and older.
Data from the Phase III TENDER study showed 85 percent (64/75) of children with systemic Juvenile Idiopathic Arthritis (sJIA) receiving ACTEMRA experienced a 30 percent improvement (JIA ACR30) in the signs and symptoms of sJIA and an absence of fever after three months of therapy, compared with 24 percent (18/37) of children receiving placebo (p<0.
And it's in phase-I trials for diabetes, but it's also planned to have phase-I trials in rheumatoid arthritis, something called SJIA, which is systemic juvenile idiopathic arthritis, and gout.

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