synaptosome

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syn·ap·to·some

(sin-ap'tō-sōm),
Membrane-bound sac containing synaptic vesicles that breaks away from axon terminals when brain tissue is homogenized under controlled conditions; such particles can be separated from other subcellular particles by differential and density gradient centrifugation.
[synapse + G. sōma, body]

synaptosome

/syn·ap·to·some/ (sin-ap´to-sōm″) any of the membrane-bound sacs that break away from axon terminals at a synapse after brain tissue has been homogenized in sugar solution; it contains synaptic vessels and mitochondria.

synaptosome

(sĭ-năp′tə-sōm′)
n.
Any of various sacs, composed of synaptic vesicles and mitochondria, that break away from axon terminals at a synapse after brain tissue has been homogenized under controlled conditions.

syn·ap′to·so′mal adj.

synaptosome

[sinap′təsōm′]
a presynaptic nerve terminal that has been separated from the rest of the neuron and isolated from homogenates of brain tissue. It appears as a membrane-bound structure containing synaptic vesicles.

syn·ap·to·some

(si-nap'tŏ-sōm)
Membrane-bound sac containing synaptic vesicles that breaks away from axon terminals when brain tissue is homogenized under controlled conditions; such particles can be separated from other subcellular particles by differential and density gradient centrifugation.
[synapse + G. sōma, body]
References in periodicals archive ?
The band at the interface of the two layers was collected and rinsed in isolation buffer, followed by centrifugation and resuspension in synaptosomal buffer (120 mM NaCl, 4.
3]H] Dopamine uptake was determined in rat striatal synaptosomal preparations based on the method detailed by Fleckenstein et al.
Syntaxin (syt), synaptobrevin (syb), and the so-called synaptosomal associated protein of 25 kDa (SNAP-25) together form an SDS-resistant heterotrimeric complex that spans the vesicle and PM, bringing the two into close proximity (i.
Inhibition by [beta]-carbolines of monoamine uptake into a synaptosomal preparation: Structure-activity relationships.
2]) for type-2 alkene adduction of cysteine sulfhydryl groups and to the respective magnitudes of in vitro synaptosomal dysfunction [toxic potency or half maximal inhibitory concentration (IC50)] (LoPachin et al.
Golimbet VE, Alfimova MV, Gritsenko IK, Lezheiko TV, Lavrushina OM, Abramova LI, Kaleda VG, Barkhatova AN, Sokolov AV, Ebstein RP Association between a synaptosomal protein (SNAP-25) gene polymorphism and verbal memory and attention in patients with endogenous psychoses and mentally healthy subjects.
Purification of the putative [alpha]-latrotoxin receptor from bovine synaptosomal membranes in an active binding form.
Lipid peroxidation associated protein damage in rat brain crude synaptosomal fraction mediated by iron and ascorbate.
The lipid composition of adult rat brain synaptosomal plasma membranes.
Evidence shows that administration of simvastatin decreases the cholesterol concentration in synaptosomal membrane and affects cholesterol distribution (Kirsch et al.
Inhibition of synaptosomal calcium uptake by ethanol.