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synaptic plasticity

   Also found in: Wikipedia 0.01 sec.
synaptic plasticity
 Physiology Malleability present in synapses in various forms–eg, presynaptic inhibition, homosynaptic depression, presynaptic facilitation and modulation of transmitter release by tonic depolarization of sensory neuron. See Neuroplasticity, Nitric oxide.


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Researchers then treated the mice with PDE inhibitors, which rescued the sleep deprivation-induced deficits in cAMP signaling, synaptic plasticity and hippocampus dependent memory.
These principles include: intensive activity maximizes synaptic plasticity, complex activities promote greater structural adaptation, activities that are rewarding increase dopamine levels and promote learning, dopaminergic neurons are highly responsive to exercise and inactivity, and when exercise is introduced at an early stage of the disease, progression can be slowed.
Dr Clea Warburton, from Bristol University's department of anatomy/MRC Centre for Synaptic Plasticity, added: "Understanding how different brain structures cooperate in producing complex memories will help provide a more accurate picture of the neurobiology of memory.
 
 
 
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