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sympatholytic

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sympatholytic /sym·pa·tho·lyt·ic/ (-lit´ik)
1. antiadrenergic; opposing the effects of impulses conveyed by adrenergic postganglionic fibers of the sympathetic nervous system.
2. an agent that so acts.

sym·pa·tho·lyt·ic (smp-th-ltk)
adj.
Opposing the physiological effects caused by stimulation of the sympathetic nervous system.

sympatholytic, sympatholytic agent.
sympatholytic [sim″pah-tho-lit´ik]
1. blocking transmission of impulses from the adrenergic (sympathetic) postganglionic fibers to effector organs or tissues, inhibiting such sympathetic functions as smooth muscle contraction and glandular secretion.
2. an agent that produces such an effect; called also antiadrenergic.

sympatholytic (sim´pthōlit´ik),
adj pertaining to a drug that blocks the effects of stimulation of the sympathetic nervous system. See also adrenolytic.

sympatholytic
antiadrenergic: blocking transmission of impulses from the adrenergic (sympathetic) postganglionic fibers to effector organs or tissues, inhibiting such sympathetic functions as smooth muscle contraction and glandular secretion. Also, an agent that produces such an effect.


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Because of its sympatholytic and vagomimetic actions, dexmedetomidine is approved with a warning about hypotension, bradycardia and sinus arrest and can be used only in a monitored situation.
The sympatholytics are also recommended because they block the peripheral autonomic hyperarousal in PTSD, but they can also cause troublesome side effects, including hypotension.
 
 
 
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