suxamethonium


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suc·ci·nyl·cho·line

(sŭk'si-nil-kō'lēn),
A neuromuscular relaxant with short duration of action that characteristically first depolarizes the motor endplate (phase I block) but is often later associated with a curarelike, nondepolarizing neuromuscular block (phase II block); used to produce relaxation for tracheal intubation and during surgical anesthesia.

suxamethonium

A short-acting depolarizing muscles relaxant commonly used immediately after inducing general anaesthesia to facilitate the insertion of an endotracheal tube. The drug is on the WHO official list. A brand name is Anectine.

suxamethonium

References in periodicals archive ?
22] found the combination of fentanyl, atropine and suxamethonium to be the most common, followed by morphine, atropine and suxamethonium.
But during more tests on Ward 20, Dr Nial McCarron wrongly used Suxamethonium instead of Lignocaine, the correct drug for the job.
The SOP included a range of induction agent options (thiopentone, etomidate and ketamine), but specified the use of suxamethonium for paralysis.
I would suggest that in this case when the airway was first lost and the patient "appeared to be splinting his chest", an appropriate dose of suxamethonium would have either resolved the issue or at least provided adequate relaxation for rescue with a laryngeal mask airway or attempted tracheal intubation (5).
Absolute indications are: replacement of single-factor deficiencies when factor concentrate was not available, immediate reversal of warfarin effect, vitamin K deficiency associated bleeding, acute disseminated intravascular coagulation (DIC), thrombotic thrombocytopenic purpura (TTP), inherited deficiencies in coagulation, and suxamethonium chloride apnoea.
Dad-of-two Stephen Parkins, 43, from Tile Cross, suffered a fatal heart attack within minutes of being wrongly injected with suxamethonium at Heartlands in 2006.
Plasma cholinesterase and abnormal reaction to suxamethonium injection: twenty years' experience with the Danish Cholinesterase Registry.
She rapidly deteriorated, developing cardiogenic shock and acute pulmonary oedema that necessitated intubation of the trachea with a rapid sequence induction technique using propofol 75 mg, fentanyl 100 [micro]g and suxamethonium 150 mg.
In 12 incidents, fentanyl was intended but suxamethonium was administered instead.
A new expert report into dadof-two Stephen Parkins, aged 43, reveals the Suxamethonium drug he received is used in torture and on death row prisoners in the US.
In particular, will anaesthetists 'switch' to rocuronium and vecuronium; is suxamethonium still necessary; and will it improve outcomes for patients?
That one of the most common errors in this study remains the substitution of suxamethonium for fentanyl, indicates the poor response in South Africa to publications identifying the problem, highlighting causative factors, and suggesting preventive measures.