susceptibility gene


Also found in: Dictionary, Thesaurus, Encyclopedia.

susceptibility gene

A gene that increases a person's likelihood of contracting a heritable illness.
See also: gene
References in periodicals archive ?
This article comprehensively reviews the latest findings on the genetics of RA, focusing mainly on the identification of novel RA susceptibility genes.
Three classes of breast cancer susceptibility genes have emerged so far.
This is exemplified in Figure 3 where the dashed gray line represents the risk profile for the most common genotypes modeled from the 12 asthma susceptibility genes (group 1 variants) and the solid blue line shows the risk profile when the NAT1 variant is added.
The researchers set out to investigate susceptibility genes for cannabis dependence, as research has already shown that it has a strong genetic component.
However, the fact that mutations in these three genes only account for approximately 25% of the familial risk of breast cancer has led to studies to identify additional breast cancer susceptibility genes (Table 1) [5].
Five years ago, scientists established that a susceptibility gene was hidden somewhere on chromosome 16.
The search for alcoholism susceptibility genes centers on two major techniques, linkage mapping and the candidate gene approach.
A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene.
It's among about 100 schizophrenia-associated genes identified through genome-wide association studies and has remained a consistent susceptibility gene using numerous other methods for examining the genetics of the disease.
Families who have an increased cancer susceptibility gene may experience people in their family developing cancer at young ages, such as in childhood, adolescence or early adulthood.
There is a very real possibility that the analysis of the genetic basis of endometriosis in this Icelandic population will lead to identification of the susceptibility gene," Dr.
Dr Doug Easton, heading the research, said: "We already know of one skin cancer susceptibility gene, but we believe there are many more.