susceptibility gene


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susceptibility gene

A gene that increases a person's likelihood of contracting a heritable illness.
See also: gene
References in periodicals archive ?
Healthcare company AstraZeneca Pharmaceuticals LP reported on Friday the receipt of approval from the US Food and Drug Administration for the expanded approval for the use of Lynparza (olaparib tablets) for the treatment of patients with germline breast cancer susceptibility gene (BRCA) mutated, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer, who have been previously treated with chemotherapy.
There is no doubt that RNF213 is a strong susceptibility gene for MMD among East Asian people.
Dr Hui said that 70 per cent of Chinese patients who had experienced severe influenza infection had the IFITM3 susceptibility gene, which could explain the emergence or presence of infection clusters among family members.
subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.
01), suggesting that the allele A was a susceptibility gene for SZ.
22) Molecular genetic approaches now provide the tools that will allow the identification of susceptibility genes.
In a study of 4,000 twins by the Department of Twin Research, scientists identified the myopia susceptibility gene RASGRF1--which has been validated in other studies comprising over 13,000 people in the UK, Netherlands and Australia.
Further, each susceptibility gene is likely to have low penetrance, thus not all carriers will develop the disorder.
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
Miklos Sahin-Toth, MD, PhD, of Boston University Goldman School of Dental Medicine and German researchers have identified chymotrypsin C (CTRC), the gene that encodes trypsin-degrading enzyme, as a susceptibility gene for the disease.
A pair of large-scale genetic studies supported by the National Institutes of Health has revealed two genes that influence the risk of getting multiple sclerosis (MS) - data sought since the discovery of the only other known MS susceptibility gene decades ago.
Examination of a single susceptibility gene can separate the study population into only two risk groups, those with and those without the mutation.