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surrogate marker

   Also found in: Wikipedia 0.01 sec.
surrogate marker
Lab medicine A parameter or measured to detect a pathologic condition when a more specific test doesn't exist, is impractical or not cost-effective; surrogate testing has been used for non-A, non-B hepatitis, measuring ALT and antibodies to HBV core antigen–anti-HBc and HC


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Since prolonged exposure to blue light is harmful to the retina, increased levels of macular pigment are considered a strong surrogate marker for protection against the processes that cause age-related blindness, including AMD," Dr.
1,2] The clinical development of superior treatment options and/or second-line therapies has been partly hampered by the lack of validated surrogate markers of treatment benefit.
There is a need for prospective studies assessing the association between periodontal disease and patients at particular risk of cardiovascular events which will allow assessment of both cardiovascular disease clinical endpoints and surrogate markers of cardiovascular risk.
 
 
 
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