surfactant protein B


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surfactant protein B

a protein crucial for surfactant function.
References in periodicals archive ?
By method of immunohistochemistry we also have found decreased expression of surfactant protein B in the majority of children with SIDS compared to infants who died of pneumonia or in accidents.
Immunohistochemistry in a significant portion of babies with the syndrome observed decrease in expression of surfactant protein B, probably due to qualitative changes in pulmonary surfactant.
It is a suspension consisting of approximately 99% phospholipids and about 1% surfactant-associated proteins, including surfactant protein B.
Surfactant protein B corrects oxygen-induced pulmonary dysfunction in heterozygous surfactant protein B-deficient mice.
Molecular and phenotypic variability in the congenital alveolar proteinosis syndrome associated with inherited surfactant protein B deficiency.
Partial deficiency of surfactant protein B in an infant with chronic lung disease.
Ultrastructure of lung in surfactant protein B deficiency.
In this Phase 2 trial, Discovery's novel surfactant, Surfaxin(TM), which contains a peptide mimic of the human surfactant protein B, was used to cleanse the lung (bronchoalveolar lavage or lung wash) and restore the surfactant inactivated by the meconium.
The peptide is KL4 (sinapultide), a 21 amino acid peptide modeled after the important human surfactant protein B.
The novel peptide, sinapultide (KL4), is a 21-amino acid peptide modeled by Scripp's scientists after human surfactant protein B (SP-B).