surfactant protein A


Also found in: Wikipedia.

surfactant protein A

a protein secreted by alveolar type II cells in the lung that regulates the secretion of surfactant, among other things.
References in periodicals archive ?
The role of surfactant protein A in acute lung injury induced by bleomycin.
Effect of surfactant protein A on lipopolysaccharide-induced tumor necrosis factor-a expression in human proximal tubular epithelial cells.
Surfactant protein A and surfactant protein D variation in pulmonary disease.
In recent years, experimental studies have emphasized that specific pulmonary bioindicators considered to be secreted from deteriorated lung tissue, such as surfactant protein A (SP-A), surfactant protein D (SP-D), Krebs von den Lungren-6 (KL-6), and Clara cell protein (CC-16), are effective in determining lung deterioration severity (29-31).
Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung, J Immunol 2000; 165: 3934-40.
Among the shared proteins were some of the most prominent blood and BAL proteins: albumin, serotransferrin, surfactant protein A (SP-A), [[alpha].
Surfactant protein A and albumin in particles in exhaled air.
Surfactant protein A (SP-A) may regulate the secretion and exocytosis of surfactant from the type II cell, as well as the re-uptake of surfactant for recycling and re-use.
Effect of hydroxylation and N187-linked glycosylation on molecular and functional properties of recombinant human surfactant protein A.
Human surfactant protein A (SP-A) may play a role in inflammation by modulating cytokine production by macrophages.
Moreover, ozone-exposed surfactant protein A (SP-A) has shown a reduced ability to bind carbohydrates and self-aggregate (6) and to inhibit phosphatidylcholine secretion by type II cells (7).