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sunitinib

   Also found in: Wikipedia 0.01 sec.
sunitinib,
a miscellaneous antineoplastic.
indications This drug is used to treat advanced renal carcinoma and GI stromal tumors after disease progression or intolerance to imatinib.
contraindications Pregnancy, lactation, and known hypersensitivity to this drug prohibit its use.
adverse effects Adverse effects of this drug include headache, dizziness, insomnia, fatigue, hypertension, altered taste, constipation, stomatitis, mucositis, skin discoloration, depigmentation of hair or skin, alopecia, pain, arthralgia, myalgia, cough, dyspnea, and electrolyte abnormalities. Life-threatening side effects include central nervous system hemorrhage, seizures, left ventricular dysfunction, hepatotoxicity, vomiting, dyspepsia, pancreatitis, neutropenia, thrombocytopenia, and bleeding. Common side effects include nausea, anorexia, abdominal pain, and rash.


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Afinitor provides an option for patients with advanced renal cell cancer after failure of treatment with the cancer therapies sunitinib or sorafenib," said Robert Justice, MD, director, Division of Oncology Products in the FDA's Center for Drug Evaluation and Research.
NICE also turned down the use of sorafenib and sunitinib (Sutent) as secondary treatment options for people with either form of the disease.
Mr Potts, of Hunter Avenue, was initially denied the "magic bullet" drug Sunitinib on the NHS but health chiefs eventually announced a U-turn and agreed to make the drug available to him.
 
 
 
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