sulphonamides


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Related to sulphonamides: Sulfa Drugs, tetracycline, Quinolones

sulphonamides

group of bacteriostatic antimicrobial drugs
References in periodicals archive ?
In our environment, where malaria is endemic, unregulated use of all antimicrobial agents is common and sulphonamide-containing anti-malarials are the preferred drug to treat malaria infection, it is possible that the effect of sulphonamide antibodies on hematological disorders (which varies with geographical location) may be different in our setting.
Sample Set size (n) Class 1 132 Estrogens 2 37 Carboquinone derivatives 3 33 Organic pollutants 4 97 Benzotriazoles 5 136 Thiophene and imidazopyridine derivatives 6 14 Substituted phenylaminoethanones 7 110 Acetylcholinesterase inhibitors 8 107 Polychlorinated biphenyl ethers 9 107 Polychlorinated biphenyl ethers 10 47 Para-substituted aromatic sulphonamides Set Property/activity 1 Estrogen binding affinity--logRBA 2 Minimum effective dose (MED) --log(1/MED) 3 Oxidative degradation--log(k') 4 Fish toxicity--pEC50 5 Inhibition of polo-like kinase 1--[pIC.
The antimicrobial agents tested were: neomycin (30[micro]g), enrofloxacin (5[micro]g), florfenicol (30[micro]g), ciprofloxacin (5[micro]g), tetracycline (30[micro]g), gentamicin (10[micro]g), nalidixic acid (30[micro]g), doxycycline (30[micro]g), nitrofurantoin (300[micro]g), chloramphenicol (30[micro]g), sulphonamide (300[micro]g) norflaxocin (10[micro]g), ampicillin (10[micro]g) and trimethoprim-sulphonamide combinations (25[micro]g).
Over the last few decades, Shigella has demonstrated unique ability to acquire horizontally-transferred genetic material, thereby making previously-efficacious drugs, like sulphonamides, tetracycline, ampicillin, and cotrimoxazole largely ineffective.
COMMON medications that can increase sun sensitivity and also cause a sun allergy include coal tar, antidepressants, antibiotics, non-steroidal anti-inflammatories and sulphonamides, but this is not an exhaustive list, explains Dr Steven Iley, medical director for AXA PPP Healthcare's specialist health services division.
Medications that can increase sun sensitivity and also cause a sun allergy include coal tar, antidepressants, antibiotics, non-steroidal anti-inflammatories and sulphonamides but this is not an exhaustive list, explains Dr Steven Iley , medical director for AXA PPP Healthcare's specialist health services division.
In this setting, sulphonamides and nevirapine are the most commonly implicated drugs.
Hence, susceptibility testing of clinically significant rapidly growing mycobacteria should be performed with antibacterial drugs like amikacin, doxycycline, imipenem, fluorquinolones, sulphonamides, cefoxitin and clarithromycin along with the conventional antitubercular drugs.
2] In the same book (edited by Fleming), however, Porritt and Mitchell made the pessimistic prophecy, 'As with sulphonamides, the prophylactic use of penicillin will carry the risk of breeding resistant strains, a matter of serious practical importance that cannot be dismissed lightly.
28) investigated the bioactivation and protein haptenation of sulphonamides, including sulfamethoxazole (SMX) and dapsone, showing the drug's metabolite and cellular protein forms a covalent product which induced the cellular toxicity.
Synthesis and urease inhibition studies of barbituric and thiobarbituric acid derived sulphonamides.