sulphonamide


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Related to sulphonamide: Sulphanilamide, sulphonamide drugs

sulphonamide

a class of organic compounds that are amides of sulphonic acids, some of which are sulpha drugs and act as powerful inhibitors of bacterial activity, although bacteria have become increasingly resistant to them. Examples are sulphadimidine and sulphadiazine.
References in periodicals archive ?
The samples in plain containers were allowed to clot and sera obtained were used to detect antibody to the sulphonamide sulfadoxine.
What may explain why the neutrophil count was significantly higher in patients with sulphonamide antibodies?
Amsacrine and sulfonylhydrazines, sulphonamide derivatives, are antineoplastic agents that are frequently used in cancer chemotherapy [5, 6].
9%) and 5% Dextrose normal saline), Phenyl butazone @ 2 mg/kg body weight IM for 3 days, Sulphonamide and Trimethoprim combination @15mg/kg b.
Persistence of sulphonamide resistance in Escherichia coli in the UK despite national prescribing restriction.
Patients were excluded from the study if they had taken less than four days of MDT or if they had been prescribed any sulphonamide drug, which could confound the results of the urine spot test.
With the increasing importance of sulphonamides, a great deal of interest has developed in the analysis of sulphonamide and efforts have been made for giving accurate and rapid procedures for their determination.
Those with a history of renal dysfunction, hypertension, sulphonamide allergy or aged more than 70 years were excluded from the trial.
Possible explanations for the persistence of sulphonamide resistance include the properties of the mobile elements on which the determinants are carried, and the possible selection pressures other than human medical use.
Optometrists should be aware of the possibility of modest myopic shifts in patients taking this drug or other sulphonamide medications.
Second, although the use of sulphonamides and trimethoprim decreased more than threefold during the study period, carriage of trimethoprim- and sulphonamide-resistant Gram-negative bacteria did not change.