sulindac


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sulindac

 [sul´in-dak]
a nonsteroidal antiinflammatory drug, used in the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, bursitis or tendinitis of the shoulder, and acute attacks of gout or calcium pyrophosphate deposition disease.

sulindac

/sul·in·dac/ (sul-in´dak)
1. a nonsteroidal antiinflammatory drug, analgesic, and antipyretic, used in treatment of rheumatic disorders.
2. a nonsteroidal antiinflammatory drug used in the treatment of various rheumatic and nonrheumatic inflammatory disorders.

sulindac

(sə-lĭn′dăk)
n.
A nonsteroidal anti-inflammatory drug used especially in the treatment of arthritis, tendinitis, and bursitis.

sulindac

[sulin′dek]
a nonsteroidal antiinflammatory agent.
indications It is prescribed in the treatment of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
contraindications Pregnancy (3rd trimester), lactation, or known hypersensitivity to this drug, aspirin, or nonsteroidal antiinflammatory drugs prohibits its use. It is used with caution in patients who have upper GI tract disease or impaired renal function.
adverse effects Among the more serious adverse reactions are GI upset, peptic ulcer, dizziness, tinnitus, and skin rash.

sulindac

Clinoril® An NSAID that binds to plasma proteins. See NSAIDs.

sulindac

A non-steroidal anti-inflammatory drug (NSAID). A brand name is Clinoril.

sulindac

non-steroidal anti-inflammatory drug used to control pain and inflammation in rheumatoid disease and other musculoskeletal disorders, including acute gout

sulindac (səlin´dak),

n brand name: Clinoril;
drug class: nonsteroidal antiinflammatory;
action: inhibits prostaglandin synthesis by interfering with cyclooxygenase, an enzyme needed for biosynthesis; possesses analgesic, antiinflammatory, and antipyretic properties;
uses: osteoarthritis, rheumatoid, acute gouty arthrits, tendinitis, bursitis, ankylosing spondylitis.
References in periodicals archive ?
Our studies show that sulindac can protect RPE cells in culture against oxidative damage, suggesting that it could be an inexpensive and relatively non-toxic therapeutic approach for treating age-related macular degeneration.
Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells.
Sulindac was shown in early-phase clinical studies to be efficacious in reducing the colorectal polyp burden (15,38,39).
Although Mutual cannot legally make sulindac in another composition," the court wrote, "the FDCA might permit states to tell Mutual it ought not to be [making sulindac] if risk-benefit analysis weights against the drug.
16) Other possible treatment options include analgesia or non-steroidal anti-inflammatory drugs like diclofenac, etodolac or sulindac.
Now, scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered how one NSAID, called Sulindac, inhibits tumor growth.
Combination cancer chemoprevention with green tea extract and sulindac shown in intestinal timor formation in Min mice.
Recent in vitro studies have revealed a number of herbal anti-oxidants such as plant lignan, nordihydroguaiaretic acid (NDGA) (119), silymarin (101), sulindac (106) and jaceosidin (102) or naturally occurring polysaccharides and glycoproteins like heparin (104), carrageenan (105), Solanum nigrum glycoproteins (107, soyasaponins (108) and Sulphated E.
1986) Renal prostaglandin E2 and F2 alpha synthesis during exercise: effects of indomethacin and sulindac.
Clinton, charged with possession of Ecstasy, dismissed, $250 costs; resisting arrest, filed with a guilty finding; and possession of sulindac with intent to distribute, dismissed.
dagger]) NSAIDs (diclofenac sodium, diclofenac potassium, diclofenac/misoprostol, etodolac, fenoprofen, flurbiprofen, ibuprofen, indomethacin, ketoprofen, ketorolac, meclofenamate, mefenamic acid, meloxicam, nabumetone, naproxen, oxaprozin, piroxicam, sulindac, tolmetin).