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sulfoxidation

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sulfoxidation,
n a phase-II detoxification pathway that occurs in the liver and in which sulfite oxidase converts sulfites, such as those found in food preservatives and colorings, garlic compounds, and chlorpromazine into sulfates so they can be safely eliminated from the body.


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Such people do not have the level of enzymes necessary to carry out the sulfoxidation necessary for a body to properly process and detoxify acetaminophen.
In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily.
2,3)) The genetic polymorphism in SCMC sulfoxidation results in the subdivision of the population into three cohorts with respect to their ability to sulfoxidize the sulfur moiety of the drug (figure).
 
 
 
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