The initial clue that led to the discovery of the RGF peptide family came from the identification of Arabidopsis tyrosylprotein sulfotransferase
(TPST) (described in section 4.
Another group of researchers found that SULT2B1 encodes sulfotransferase
family 2B member 1 and is central to epidermal cholesterol metabolism (Am J Hum Genet.
CYP3A4) and different sulfotransferase
and uridine diphospho-glucuronosyltransferase (UGT) enzymes, as compared to the human small intestine, also makes Caco-2 cells a poor model for studying intestinal metabolism (Gregory et al.
(SULT) enzymes metabolize various substrates.
Furthermore, the polymorphism reducing the activity of sulfotransferase
which triggers the development of UTUC is the only genetic etiological factor described in the literature (4).
Characterization of porcine uterine estrogen sulfotransferase
Indeed, at least in rats, a sulfotransferase
has been identified for
1N, STM3191, STM4431, fucP, STM0326 and STM1553) showed considerable structural homology with bacterial 2-dehydro-3-deoxy-6-phosphogalactonate aldolase, aryl sulfate sulfotransferase
, acetohydroxy-acid synthase, L-fucose transporter, glycerol dehydratase activator and paired box proteins respectively (Fig.
Ung D, Nagar S (2007) Variable sulfation of dietary polyphenols by recombinant human sulfotransferase
(SULT) 1A1 genetic variants and SULT1E1.
1000] covers phase II detoxification enzymes that include glutathione S-transferse, sulfotransferase
1a1, betainehomocysteine methyltransferase 2, and UDP glucuronosyltransferease 1A1.
We observed that cytosolic PAPSS2 supported DHEA sulfation by cytoplasmic sulfotransferase
SULT2A1 to a larger extent than cytosolic PAPSS1.
Although relatively little is known about placental EtS transfer, evidence of variable yet substantial fetal sulfotransferase
activity (25) suggests that meconium EtS may be of fetal origin.