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sulfotransferase

   Also found in: Wikipedia 0.01 sec.
sul·fo·trans·fer·ase (slf-trnsf-rs, -rz)
n.
An enzyme that catalyzes the transfer of a sulfate group from one compound to the hydroxyl group of another.


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Sulfotransferase (SULT) 1A1 polymorphic variants *1, *2, and *3 are associated with altered enzymatic activity, cellular phenotype, and protein degradation.
The genotoxicity of IQ depends on its metabolic activation to reactive intermediates by a two-step process involving N-hydroxylation by CYP1A2, followed by esterification of N-hydroxylamine by N-acetyltransferase or sulfotransferase to reactive ester derivatives that covalently modify DNA (Schut and Snyderwine, 1999).
Reversible Covalent Inhibition of a Phenol Sulfotransferase by Coenzyme A.
 
 
 
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