Sulfonamide

sulfonamide /sul·fon·amide/ (sul-fon´ah-mid) a compound containing the sbondSO2NH2 group. The sulfonamides, or sulfa drugs, are derivatives of sulfanilamide, competitively inhibit folic acid synthesis in microorganisms, and formerly were bacteriostatic against a wide variety of bacteria and some protozoa. Because many microbes are now resistant, sulfonamides have largely been supplanted by more effective and less toxic antibiotics.

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sul·fon·a·mide (sl-fn-md, -md)

n.

1. Any of a group of organic sulfur compounds that includes the sulfa drugs.

2. See sulfa drug.

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Sulfonamide

A sulfa drug, one of a large group of drugs used to treat bacterial infections.

Mentioned in: Serum Sickness

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sulfonamide (sulfon´mīd),

n a derivative of sulfanilamide that is effective against microorganisms.

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sulfonamide

1. any compound containing the -SO₂NH₂ group.

2. any of a group of drugs that are derivatives of sulfanilamide, which competitively inhibit folic acid synthesis in microorganisms, and are bacteriostatic against gram-positive cocci (streptococci and pneumococci), gram-negative cocci (meningococci and gonococci), gram-negative bacilli (Escherichia coli and shigellae), and a wide variety of other bacteria. Sulfonamides have been supplanted by more effective and less toxic antibiotics in most uses. Called also sulfa drugs.