sulfhydryl


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Related to sulfhydryl: Sulfhydryl group

sulfhydryl

 [sulf-hi´dril]
the univalent radical -SH.

sulf·hy·dryl (SH),

(sŭlf-hī'dril),
The radical -SH; contained in glutathione, cysteine, coenzyme A, and lipoamide (all in the reduced state), and in mercaptans (R-SH).
Synonym(s): thiel

sulfhydryl

/sulf·hy·dryl/ (sulf-hi´dril) the univalent radical, —SH.

sulf·hy·dryl

(SH) (sŭlf-hī'dril)
The radical -SH; contained in glutathione, cysteine, coenzyme A, lipoamide (all in the reduced state), and in mercaptans (R-SH).
Synonym(s): sulph-hydryl.

sulfhydryl

the univalent radical, −SH.

sulfhydryl compounds
compounds which contain sulfhydryl groups, principally the sulfur-containing amino acids. Used as radioprotective agents.
References in periodicals archive ?
These processes include metallothionein activity and the reactivity of various cell ligands with high affinity for heavy metals, including sulfhydryl, hydroxyl, carboxyl, imidazole, and amino residues of proteins, and lowmolecular weight thiols; and the formation of mineralized secretory lysosomes and related vesicle structures (Viarengo & Nott 1993).
They first performed some biochemistry experiments to determine whether these sulfhydryl groups can form disulfide bonds-they can.
The key is the nucleophilic sulfhydryl group, which initiates hydrolysis of the silicon alkoxide.
Table 1: ICH Topic Q6 B (Specifications: test procedures and acceptance criteria for biotechnological/biological products) Appendix for Physiochemical Characterization Structural characterization and confirmation a) Amino acid sequence b) Amino acid composition c) Terminal amino acid sequence d) Peptide map e) Sulfhydryl groups and disulphide bridges f) Carbohydrate structure Physicochemical properties --Molecular weight or size --Isoform pattern --Extinction coefficient --Electrophoretic patterns --Liquid chromatographic patterns --Spectroscopic profiles
The hydroxyl radical wreaks havoc by reacting with lipids in cellular membranes, nucleotides in DNA, and tyrosine and sulfhydryl groups in proteins.
Angiogen recognized that combining two FDA-approved drugs - a plasminogen activator, such as urokinase, and a free sulfhydryl donor used to treat high blood pressure - could generate a proprietary anti-cancer treatment.
It is an essential part of SOD and protects vital biomolecules called sulfhydryl compounds from oxidizing and turning into free radicals.
153-158) Specifically, it has been shown that sulfhydryl compounds limit geatamicin-induced damage to outer hair cells in vitro and that in vivo gentamicin ototoxicity can be diminished with glutathione.
Fragments of furin containing the aforementioned cysteine residues were isolated and tagged with iodoacetamide, which attaches to the free sulfhydryl group in cysteine residues not involved in a disulfide bond.
Here's how it works: Ionic silver has an affinity for hydrogen ions, joining with them on the sulfhydryl groups present in the microbes, disrupting electron transfer and respiration in the microbes.
Heterobifunctional cross-linkers possess two different reactive groups that can allow for sequential conjugations with specific groups, such as the amines and sulfhydryl groups of proteins.