sulfanilamide


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sulfanilamide

 [sul″fah-nil´ah-mīd]
a potent antibacterial compound. Although replaced as a systemic agent by more effective and less toxic derivatives, and by antibiotics; it is still used vaginally in the treatment of vulvovaginal candidiasis.

sul·fa·nil·a·mide

(sŭl'fă-nil'ă-mīd),
The first sulfonamide used for its chemotherapeutic effect in infections.

sulfanilamide

(sŭl′fə-nĭl′ə-mīd′, -mĭd)
n.
A white, odorless crystalline sulfonamide, C6H8N2SO2, used in the treatment of various bacterial infections.

sulfanilamide

[sul′fah-nil′ah-mīd]
a potent antibacterial compound. Although replaced as a systemic agent by more effective and less toxic derivatives and by antibiotics, it is still used vaginally in the treatment of vulvovaginal candidiasis.

sulfanilamide

a potent antibacterial compound, the first of the sulfonamides, the first real antibacterial and the drug that opened the door into the antibiotic era.
References in periodicals archive ?
The 1937 Elixir Sulfanilamide Incident, 15 FDA CONSUMER 18 (1981), available at http://www.
While there, he experimented with dyes as antibiotics and discovered that a dye component, sulfanilamide, killed strep and tuberculosis bacteria.
Sulfanilamide was released in the US in 1936, when safety and efficacy studies were not required; the sole FDA requirement was that the product label list all active ingredients.
The next big change was the discovery of anti-infectives, sulfanilamide in 1935 and penicillin in 1940.
Standard solutions of N-(1-naphthyl) ethylenediamine dihydrochloride (NED), sulfanilamide, glycine, L-aspartic acid, sodium nitrite, urea, ethylenediaminetetraacetic acid disodium salt (EDTA), ammonium chloride, L-glutamic acid sodium salt and L-arginine, each containing 5 mg N/L, were used to determine N recovery (against KN[O.
This philosophy emerged after drug disasters such as those involving elixer sulfanilamide and thalidomide revealed the harm that could come from inadequate government controls.
They often mention a 1901 diphtheria outbreak in which thirteen children died from a flawed remedy or the "Elixir Sulfanilamide tragedy" of the 1930s (out of which the Food, Drug, and Cosmetic Act was born) in which more than one hundred people, most of them children, died.
Gonococcal resistance has been ongoing since the 1940s, starting with resistance to sulfanilamide.
After a long legislative fight, the Act was signed into law following public awareness of the tragedy surrounding sulfanilamide.
Phototoxic photosensitivity: tetracyclines, sulfanilamide, chlorpromazine, psoralens
82) In 1941, the year that Roosevelt issued the first executive order prohibiting discrimination on grounds of race, color, creed, or nationality in federal contracts, (83) doctors successfully treated trachoma and pneumonia with sulfanilamide, and Cheerios appeared for the first time on American breakfast tables.