sulfadoxine


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sulfadoxine

 [sul″fah-dok´sēn]
a long-acting sulfonamide used in combination with pyrimethamine in the prophylaxis and treatment of malaria caused by chloroquine-resistant strains of Plasmodium falciparum.

sulfadoxine

/sul·fa·dox·ine/ (-dok´sēn) a long-acting sulfonamide used in combination with pyrimethamine in the prophylaxis and treatment of chloroquine-resistant falciparum malaria.

sulfadoxine

[sul′fah-dok′sēn]
a long-acting sulfonamide used in combination with pyrimethamine in the prophylaxis and treatment of malaria caused by chloroquine-resistant strains of Plasmodium falciparum. See also antimalarial.

sulfadoxine

A SULPHONAMIDE DRUG drug used as an adjunct to CHLOROQUINE in the treatment of Falciparum MALARIA. A brand name is Fansidar.

sulfadoxine

a long-acting sulfonamide. Called also sulformethoxine.
References in periodicals archive ?
The samples in plain containers were allowed to clot and sera obtained were used to detect antibody to the sulphonamide sulfadoxine.
Quantitation of Fansimef components (mefloquine + sulfadoxine + pyrimethamine) in human plasma by two high-performance liquid chromatographic methods.
The authors were surprised that an extra dose of sulfadoxine pyrimethamine made such a difference to outcomes.
Others received pills combining sulfadoxine and pyrimethamine, an old, inexpensive therapy still used extensively in Africa (SN: 11/11/06, p.
Chloroquine and quinine have "very limited use" for SBET, while other drugs such as mefloquine, atovaquone and proguanil (Malarone), and sulfadoxine plus pyrimethamine (Fansidar) are acceptable for SBET.
The following drugs were checked: acetylsalicylic acid, acetaminophen, ibuprofen, dextropropoxyphen, fluoxetine hydrochloride, bromazepam, oxazepam, zolpidem, pindolol, atenolol, digoxin, meprobamate, theophylline, valproic acid, chloroquine, quinine, amodiaquin, mefloquine, sulfadoxine, and pyrimethamine.
In these transmission contexts, IPTp, the preventive treatment of all pregnant women with curative regimens of sulfadoxine pyrimethamine (SP) during the second and third trimesters, can decrease both placental malaria parasitemia and maternal anemia (13).
Pyrimethamine sulfadoxine resistance in Plasmodium falciparum: what next?
Sulfadoxine and pyrimethamine are not normally used as prophylaxis for any patient, due to the risk of toxic epidermal necrolysis and Stevens-Johnson syndrome, and the possible risk of jaundice and kernicterus if used in the third trimester of pregnancy.
Malawi abandoned the drug in 1993, and doctors there replaced it with an inexpensive combination pill containing sulfadoxine and pyrimethamine.
Chloroquine and quinine have "very limited use" for SBET, while drugs such as mefloquine, atovaquone and proguanil (Malatone), and sulfadoxine plus pyrimethamine (Fansidar) are acceptable for SBET.