succinimide


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suc·cin·i·mide

(suk-sin'ă-mīd),
Chemical class of drugs from which the antiepileptic agents ethosuximide, methsuximide, and phensuximide are derived. Unsubstituted succinimide has been used as an antiurolithic.

succinimide

/suc·ci·ni·mide/ (suk-sin´ĭ-mīd)
1. an organic compound comprising a pyrrole ring with two carbonyl substitutions.
2. any of a class of anticonvulsants with such a basic structure.
References in periodicals archive ?
Polyether amines, polyisobutylene amines, and polyisobutylene succinimides as fuel additives reduce the intake valve deposit by 45-60% from the base fuel and lower somewhat the combustion chamber deposit when compared to the base fuel.
The spectra show details of the characteristic peak pattern of the compound polyisobutylene succinimide (PIBSI; figure 8).
20], found that increase of amino groups in polar anchoring part of succinimide dispersant increase the adsorption affinity of dispersant onto the adsorbing surface which plays an important role in the stability of the suspensions.
Succinimide is an important raw material or intermediate in chemical synthesis, it can be used to produce N-halogen succinimide,silver cyanide-free electroplating.
The major part of yet another patent owned by Infineum, EP 0807155, which was for diesel fuel containing succinimide detergents and ester lubricity enhancers, was also revoked by the EPO last November following proceedings brought by two opponents, including Innospec.
The immunoRCA conjugate consisted of monoclonal anti-human IgE antibody (PharMingen), activated with the heterobifunctional cross-linking agent N-[[gamma]-maleimidobutyryloxy] succinimide ester, conjugated to a 40mer thiolated oligonucleotide primer, and purified as described previously (9).
To make Elg fibers, the succinimide ester was reacted for 1 h with 0.
Propensity for spontaneous succinimide formation from aspartyl and asparaginyl residues in cellular proteins.
0 to AP (2 g/L) by use of a 60-fold excess of a 30-atom heterobifunctional linker molecule based on a succinimidyl-4-(N-maleimidomethyl) cyclohexane-1-carbonate parent compound in which the terminal succinimide groups are separated by a 30-atom spacer arm.
In contrast, first-generation AEDs that do not appear to be associated with a significant risk of birth defects include the benzodiazepines (clonazepam [Klonopin], clorazepate [Tranxene], diazepam [Valium], and lorazepam [Ativan]) and succinimides (ethosuximide [Zarontin] and methsuximide [Celontin]).
The succinimides consist of ethosuximide, methsuximide and phensuximide.