succinate-semialdehyde dehydrogenase - definition of succinate-semialdehyde dehydrogenase in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.

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succinate-semialdehyde dehydrogenase /suc·ci·nate-semi·al·de·hyde de·hy·dro·gen·ase/ (sem?e-al´de-hid de-hi´dro-jen-as?) an oxidoreductase catalyzing the final step in ?-aminobutyric acid (GABA) inactivation; deficiency (succinic semialdehyde dehydrogenase deficiency) causes increased levels of GABA and ?-hydroxybutyric acid in urine, plasma, and cerebrospinal fluid, mental retardation, hypotonia, and ataxia.

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