succinate


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Related to succinate: Doxylamine succinate, Sumatriptan succinate

succinate

 [suk´sĭ-nāt]
any salt, ester, or anionic form of succinic acid.

suc·ci·nate

(sŭk'si-nāt),
A salt of succinic acid.

succinate

/suc·ci·nate/ (suk´sĭ-nāt) any salt or ester of succinic acid.
succinate semialdehyde  γ.
Succinateclick for a larger image
Fig. 292 Succinate . Molecular structure.

succinate (succinic acid)

a 4-carbon DICARBOXYLIC ACID found in the KREBS CYCLE (see Fig. 292 ). It is formed from succinyl CoA by the ENZYME succinyl CoA synthetase. This is the only step in the cycle that directly yields a high energy bond. Succinate is subsequently oxidized to fumarate by the enzyme succinate DEHYDROGENASE.

succinate

any salt of succinic acid.

succinate dehydrogenase
an enzyme of the TCA cycle, located in the inner mitochondrial membrane that splits off hydrogen from succinic acid.
References in periodicals archive ?
dramatically advanced our understanding of impaired succinate pathways in reperfusion ischemic injury, whereas no evidence for similar impairment was developed in the 2004 study.
It is interesting that apart from the major metabolites formate, acetate, lactate, ethanol and succinate as reported previously, citrate ([delta] = 2.
However, Succinate dehydrogenase activity was recorded rich in the species of Rhodophyceae which shown the range of 0.
Succinate is traditionally manufactured from petrochemicals through expensive processes.
In January 2005, the company announced FDA acceptance of its sumatriptan succinate injection Abbreviated New Drug Applications (ANDA) with Paragraph IV Certification.
The 35 patients in group 2 received 250 mg of methyiprednisolone sodium succinate intraoperatively 5 minutes prior to ligating the pulmonary artery
Researchers found that the energy-releasing enzyme, succinate dehydrogenase, acts like a catalytic converter to clear toxic pollution in the body.
Our working hypothesis is that tryptamine inhibits succinate dehydrogenase (SDH), a Krebs cycle enzyme that converts succinate to fumerate ultimately increasing ATP levels.
Taking 400 IU of vitamin E succinate (or any other dry or water-soluble form of the vitamin, which is best absorbed) twice a day may improve your memory.
Succinate dehydrogenase (SDH) has frequently been used as a qualitative histochemical marker for the presence of "ragged-red fibers" in skeletal muscle, which indicates abnormally increased numbers of mitochondria; this defect also is detected by the modified Gomori trichrome stain.
The patents cover SDDs made with an active pharmaceutical ingredient (API) and hydroxypropyl methylcellulose acetate succinate (HPMCAS), a polymer that is also known as hypromellose acetate succinate.
doxylamine succinate, pyridoxine hydrochloride) Delayed-Release Tablets for the treatment of Nausea and Vomiting of Pregnancy (NVP),[sup.