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succimer

   Also found in: Wikipedia 0.01 sec.
succimer /suc·ci·mer/ (suk´sĭ-mer) a heavy metal–chelating agent that is an analogue of dimercaprol, used in the treatment of lead poisoning; also complexed with technetium Tc 99m and used in renal function testing.
Succimer (Chemet)
A drug used to remove excess lead from the body.
Mentioned in: Lead Poisoning

succimer [suk´sĭmer]
a chelating agent that is an analogue of dimercaprol, administered orally in the treatment of heavy metal poisoning. A complex with technetium 99m is used in renal function testing.

succimer
A water-soluble chelator administered per os for heavy metal poisoning–eg, lead poisoning in children > 2.17 µmol/L–US: 45 µg/dl or adults with lead poisoning due to gunshot wounds. See Lead, Saturnine gout.


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The effect of chelation therapy with succimer on neuropsychological development in children exposed to lead.
He was chelated with succimer (dimercaptosuccinic acid, or DMSA), but chelation was discontinued because of an adverse dermatologic response.
A recent double-blind randomized clinical trial of oral chelation in young children with blood lead concentrations ranging from 22 to 44 [micro]g/dL found that the drug succimer lowered blood concentrations transiently but did not improve cognitive function (Dietrich et al.
 
 
 
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