subtherapeutic


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subtherapeutic

(sŭb′thĕr-ə-pyo͞o′tĭk)
adj.
Below the dosage levels used to treat diseases: subtherapeutic feeding of penicillin to livestock.

sub′ther·a·peu′ti·cal·ly adv.

subtherapeutic

(sŭb″thĕr-ŭ-pūt′ĭk) [″ + ″]
1. Less than adequately treated.
2. Taking a drug with a blood level below a desired treatment range. Patients using warfarin for atrial fibrillation, for example, have subtherapeutic anticoagulation when their international normalized ratio (INR) is below 2.0.
References in periodicals archive ?
Here, the interaction of liraglutide and teneligliptin with subtherapeutic anti-inflammatory dose of ibuprofen was evaluated Table 2.
28) The physicians called for ending the use of subtherapeutic use of antibiotics in food production.
4) Failure to receive drugs 00 (00) Improper drug selection 00 (00) Subtherapeutic dose 00 (00) Over dosage 00 (00) Total 137 DRP: Drug-related problems, ADRs: Adverse drug reactions Table 8: DRPs according to gender DRP Male (%) Female (%) Total (%) With DRPs 32 (45.
This included 28,583 who were not taking any antithrombotic treatment, 12,751 who were taking subtherapeutic doses of warfarin (international normalized ratio (INR) of less than 2 at the time of their stroke), and 37,674 who were taking only antiplatelet drugs when additional treatment was indicated, the investigators said (JAMA.
Distribution and characterization of ampicillin-and tetracycline- resistant Escherichia coli from feedlot cattle fed subtherapeutic antimicrobials.
In the dose-reduction group, no patients receiving TMP/SMX developed a subtherapeutic INR, whereas 40% (4 of 10 patients) who received levofloxacin developed a subtherapeutic INR.
Although antibiotics are usually added to feed, water, or both at subtherapeutic levels, at some feedlots, chlortetracycline and oxytetracycline are used at therapeutic levels to prevent infection, particularly when calves are first introduced into feedlots (6).
The rest were either subtherapeutic at 15-500 ng/mL or had no detectable hydroxychloroquine in their blood.
If the vials administered to the patient were similarly compromised, the patient would have received a subtherapeutic dose of ceftriaxone, which might have contributed to treatment failure (7).
The tenfold higher concentration corresponded to 5120 pg/ml STW 5, which is still subtherapeutic, representing one tenth of the recommended therapeutic dose of 51.
Furthermore, a lack of efficacy caused by efforts to circumvent patents protecting formulations or processes may result in subtherapeutic levels of medicines, resulting in obvious health risks.
It's more expensive to raise an antibiotic-free bird than it is to raise a bird that you feed subtherapeutic levels of antibiotics.