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subclone

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subclone /sub·clone/ (sub´klōn)
1. the progeny of a mutant cell arising in a clone.
2. each new DNA population produced by cleaving DNA from a clonal population into fragments and cloning them.


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From the variety of cell phenotypes expressed after differentiation from the NT2 cell line, we sought to subclone a human neuronal cell line from the NT2 heritage that was specific to the synthesis and secretion of GABA, characterize these cells in vitro, and test cell therapy with them in an SCI pain model.
Among these strains is a highly virulent subclone of serotype M1T1 that has exhibited unusual epidemiologic features and virulence, unlike all other streptococcal strains.
 
 
 
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