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subacute combined degeneration

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subacute combined degeneration
Subacute combined degeneration of the spinal cord Neurology A disorder caused by vitamin B12 deficiency, characterized by weakness, sensory defects, mental changes, vision defects, often associated with megaloblastic anemia Clinical SCD causes demyelination, affecting the spinal cord, brain, optic and peripheral nerves, with axonal destruction. See Vitamin B12 deficiency.


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To the Editor: Subacute combined degeneration (SCD) of the spinal cord arises from deficiency of cobalamin and may be induced by pernicious anemia (PA) which typically affects patients of Northern European ancestry and tends to occur in the sixth decade of life.
 
 
 
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