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motif
(redirected from structural m's)

   Also found in: Dictionary/thesaurus, Legal, Encyclopedia 0.03 sec.
motif
for proteins a three-dimensional structural unit formed by a particular sequence of amino acids, found in proteins and which is often linked with a particular function. For nucleic acids a particular, usually short, nucleotide sequence that forms a recognition site usually to which other proteins bind.

structural m's
in proteins, certain specific orderings of secondary structure that may have a functional role and include β-α-β helix-turn-helix, leucine zippers, calcium binding EF hands, zinc fingers and longer orderings that take on a structural domain such as the β-barrel and the immunoglobulin fold.

Patient discussion about motif.

Q. What other illnesses are similar to asthma? I am 45 years old. My doctor suspects I might have adult asthma but there has yet been a final diagnosis made. What other problems might this be?

A. Before diagnosing someone as asthmatic, alternative possibilities should be considered. A clinician taking a history should check whether the patient is using any known bronchoconstrictors (substances that cause narrowing of the airways, e.g., certain anti-inflammatory agents or beta-blockers). Chronic obstructive pulmonary disease, which closely resembles asthma, is correlated with more exposure to cigarette smoke, an older patient, and decreased likelihood of family history of atopy. Your physician should examine these possibilities as well before diagnosing.

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