streptozocin /strep·to·zo·cin/ (-zo´sin) an antineoplastic antibiotic derived from Streptomyces achromogenes; used principally in the treatment of islet cell and other tumors of the pancreas.
streptozocin
streptozocin [strep″to-zo´sin]
strep·to·zo·cin (str p t -z  s n) or strep·to·zot·o·cin (-z t-sn)n. An antineoplastic agent produced by an actinomycete and active against tumors but damaging to insulin-producing cells and now regarded as a carcinogen. |
streptozocin
[strep′təzō′sin]
an antineoplastic used in the treatment of neoplasms, including metastatic islet cell tumors of the pancreas. It is an antibiotic substance from Streptomyces acromogenes.
streptozocin [strep″to-zo´sin]
an antitumor antibiotic derived from Streptomyces achromogenes, now produced synthetically. It contains a nitrosourea group linked to a methyl group and a glucosamine moiety and acts as an alkylating agent to inhibit DNA synthesis, and also as an inhibitor of enzymes involved in gluconeogenesis; used primarily for treatment of islet cell carcinoma of the pancreas and other endocrine tumors including gastrinomas associated with zollinger-ellison syndrome and glucagon-secreting alpha cell tumors of the pancreas.
streptozocin, streptozotocin
a nitrosurea compound with antineoplastic activity, derived from Streptomyces achromogenes; used principally in the treatment of islet-cell tumors of the pancreas.
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