streptomycin /strep·to·my·cin/ (-mi´sin) an aminoglycoside antibiotic produced by Streptomyces griseus and effective against a wide variety of aerobic gram-negative bacilli and some gram-positive bacteria, including mycobacteria, but to which many of the former have developed resistance; used as the sulfate salt in the treatment of tuberculosis, tularemia, plague, and brucellosis.
streptomycin (strep´tōmī´sin),
streptomycin
strep·to·my·cin or strep·to·my·cin A (str p t -m  s n)n. An antibiotic obtained from Streptomyces griseus and used against the tubercle bacillus and other bacteria. |
streptomycin (strep´tōmī´sin),
n an antimicrobial drug often used to treat infections caused by gram-negative bacteria (such as tuberculosis). Though no human studies have been conducted, streptomycin administered during pregnancy or breastfeeding may cause damage to the ear of the fetus or infant.
streptomycin
one of the oldest of the aminoglycoside antibiotics. Because of its widespread use many previously susceptible gram-negative bacteria have developed a resistance to it and it has lost a great deal of its effectiveness and popularity. It is most effective against leptospira and haemophilus-associated infections. Like all other members of the group, streptomycin is absorbed poorly from the alimentary tract and must be given parenterally, usually by intramuscular injection for systemic effect. The group has moderate toxicity but this is of minor importance in food animals. Even in companion animals the risk is small but deafness and vestibular disturbances can occur, particularly in cats. Dihydrostreptomycin is a derivative and is used as an alternative to the parent antibiotic.
streptomycin
Infectious disease An antibiotic used for TB Adverse effects N&V, dizziness, rash, fever, ototoxicity, nephrotoxicity
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