streptokinase-streptodornase

streptokinase /strep·to·ki·nase/ (-ki´nās) a protein produced by β, which produces fibrinolysis by binding to plasminogen and causing its conversion to plasmin; used as a thrombolytic agent.

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streptokinase-streptodornase  (SKSD) a mixture of enzymes elaborated by hemolytic streptococci; used as a proteolytic and fibrinolytic agent.

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streptokinase-streptodornase

n.

A purified mixture containing streptokinase, streptodornase, and other proteolytic enzymes. It is used by topical application, or by injection into body cavities, to remove clotted blood and fibrinous and purulent accumulations of exudate.

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streptokinase-streptodornase

[-strep′tōdôr′nās]

two enzymes derived from a strain of Streptococcus hemolyticus.

indications It is prescribed for debridement of purulent exudates, clotted blood, radiation necrosis, or fibrinous deposits resulting from trauma or infection.

contraindications Active hemorrhage, acute cellulitis, or danger of reopening bronchopleural fistulas prohibits its use.

adverse effects Among the more serious adverse effects are pyrogenic reactions and irritation.

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streptokinase [strep″to-ki´nās]

an enzyme produced by streptococci that catalyzes the conversion of plasminogen to plasmin. It is administered intravenously as a thrombolytic agent in the treatment of acute coronary arterial thrombosis, acute pulmonary embolism, deep venous thrombosis, and acute arterial thromboembolism or thrombosis. It is also used to clear obstructed arteriovenous cannulae. Detailed and skilled control is required in its use in order to avoid hemorrhage. It also can produce severe antigenic reactions upon readministration. See also anticoagulant.

streptokinase-streptodornase a mixture of enzymes elaborated by hemolytic streptococci; used as a proteolytic and fibrinolytic agent.

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streptokinase-streptodornase,

n.pl two enzymes derived from a strain of
S. hemolyticus. It is prescribed for debridement of purulent exudates, clotted blood, radiation necrosis, or fibrinous deposits resulting from trauma or infection.

Streptomyces

n a genus of gram-positive, funguslike bacteria belonging to the order actinomycetales. Several antibiotics, such as tetracyclines and aminoglycosides, are produced from them.

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streptokinase

an enzyme produced by streptococci that catalyzes the conversion of plasminogen to plasmin; abbreviated SK. Streptokinase, when administered as a thrombolytic, requires detailed and skilled control to avoid hemorrhage. It also is capable of producing severe antigenic reactions upon readministration. See also anticoagulant (2).

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streptokinase-streptodornase

a mixture of enzymes elaborated by hemolytic streptococci; used as a proteolytic and fibrinolytic agent.