exotoxin (redirected from streptococcal pyrogenic exotoxin)

exotoxin /exo·tox·in/ (ek´so-tok″sin) a potent toxin formed and excreted by the bacterial cell, and free in the surrounding medium.ex´otoxic

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streptococcal pyrogenic exotoxin  one produced by Streptococcus pyogenes, existing in several antigenic types and causing fever, the rash of scarlet fever, organ damage, increased blood-brain barrier permeability, and alterations in immune response.

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ex·o·tox·in (ks-tksn)

n.

A toxin secreted by a microorganism and released into the environment in which it grows. Also called extracellular toxin.

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Exotoxin

A poisonous secretion produced by bacilli which is carried in the bloodstream to other parts of the body.

Mentioned in: Diphtheria

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exotoxin

[ek′sətok′sin]

Etymology: Gk, exo + toxikon, poison

a toxin that is secreted or excreted by a living microorganism. Compare endotoxin.

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exotoxin [ek´so-tok″sin]

a potent toxin formed and excreted by the bacterial cell and found free in the surrounding medium; exotoxins are the most poisonous substances known. They are protein in nature and heat labile, and are detoxified with retention of antigenicity by treatment with formaldehyde. Bacteria of the genus Clostridium are the most frequent producers of exotoxins; diphtheria, botulism, and tetanus are all caused by such toxins. adj., adj ex´otoxic.

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exotoxin (ek´sōtoksin),

n the toxic material formed by microorganisms and subsequently released into their surrounding environments.

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exotoxin

a potent toxin formed and secreted by the bacterial cell, and found free in the surrounding medium.

Exotoxins are generally heat labile, and are protein in nature. Many can be detoxified with retention of antigenicity by treatment with formaldehyde (toxoid). Many are important virulence factors in pathogenic bacteria.