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storage pool diseases

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storage pool diseases
Metabolic disease A group of platelet disorders caused by defects of platelet granules, divided into 1. α granule storage pool disease. See Gray platelet syndrome and 2. Dense granule deficiency or delta-storage pool disease Clinical Moderate bleeding Lab ↑ Bleeding time, ↓ platelet ADP content, ↓ serotonin levels Treatment Hemostasis with platelet transfusions, cryoprecipitate, desmopressin acetate–DDAVP, which releases von Willebrand factor from storage sites


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